Publikationer

2012

Rosengren AM, Karlsson BCG, Nicholls IA. Monitoring the Distribution of Warfarin in Blood Plasma. ACS Medicinal Chemistry Letters (2012) in press DOI:10.1021/ml300112e

Andersson HS, Figueredo SM, Haugaard-Kedström LM, Bengtsson E, Daly NL, Qu X, Craik DJ, Ouellette AJ, Rosengren KJ. The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids (2012) 1-13 DOI:10.1007/s00726-012-1220-3

Schillinger E, Möder M, Olsson GD, Nicholls IA, Sellergren B. An Artificial Estrogen Receptor Via Combinatorial Imprinting. Chemistry - A European Journal (2012) 18:14773-14783 DOI:10.1002/chem.201201428

Olsson GD, Karlsson BCG, Shoravi S, Wiklander JG, Nicholls IA. Mechanisms Underlying Molecularly Imprinted Polymer Molecular Memory and The Role of Crosslinker: Resolving Debate on the Nature of Template Recognition in Phenylalanine Anilide Imprinted Polymers. Journal of Molecular Recognition (2012) 25:69-73

Nicholls IA, Andersson HS, Golker K, Henschel H, Karlsson BCG, Olsson GD, Rosengren AM, Shoravi S, Wiklander JG, Wikman S. Rational molecularly imprinted polymer design: theoretical and computational strategies. (2012) In: Molecularly Imprinted Polymers in Analytical Science, Ye L. (ed), Pan Stanford Publishing, in press

2011

Ekdahl KN, Lambris JD, Elwing H, Ricklin D, Nilsson PH, Teramura Y, Nicholls IA, Nilsson B. Innate immunity activation on biomaterial surfaces: A mechanistic model and coping strategies. Advanced Drug Delivery Reviews (2011) 63:1042-1050.

Henschel H, Kirsch N, Hedin-Dahlström J, Whitcombe MJ, Wikman S, Nicholls IA. Effect of the cross-linker on the general performance and temperature dependent behaviour of a molecularly imprinted polymer catalyst of a Diels-Alder reaction. Journal of Molecular Catalysis B: Enzymatic (2011) 72:199-205.

Nicholls IA, Andersson HS, Golker K, Henschel H, Karlsson BCG, Olsson GD, Rosengren AM, Shoravi S, Suriyanarayanan S, Wiklander JG, Wikman S. Rational design of biomimetic molecularly imprinted materials: theoretical and computational strategies for guiding nanoscale structured polymer development. Analytical and Bioanalytical Chemistry (2011) 400:1771-1786.

Wiklander J, Karlsson BCG, Aastrup T, Nicholls IA. Towards a synthetic avidin mimic. Analytical and Bioanalytical Chemistry (2011) 400:1397-1404.

Haugaard-Kedström LM, Shabanpoor F, Hossain MA, Clark RJ, Ryan PJ, Craik DJ, Gundlach AL, Wade JD, Bathgate RAD, Rosengren KJ. Design, Synthesis, and Characterization of a Single-Chain Peptide Antagonist for the Relaxin-3 Receptor RXFP3. Journal of the American Chemical Society (2011) 133:4965-4974.

Daly NL, Rosengren KJ, Henriques ST, Craik DJ. NMR and protein structure in drug design: application to cyclotides and conotoxins. European Biophysics Journal with Biophysics Letters (2011) 40:359-370.

Rosengren AM, Karlsson BCG. Spectroscopic evidence for the presence of the cyclic hemiketal form of warfarin in aqueous solution: Consequences for bioavailability. Biochemical and Biophysical Research Communications (2011) 407:318-320.

Rosengren AM, Karlsson BCG, Näslund I, Andersson PO, Nicholls IA. In situ detection of warfarin using time-correlated single-photon counting. Biochemical and Biophysical Research Communications (2011) 407:60-62.

Engberg AE, Rosengren-Holmberg JP, Chen H, Nilsson B, Lambris JD, Nicholls IA, Ekdahl KN. Blood protein-polymer adsorption: Implications for understanding complement-mediated hemoincompatibility. Journal of Biomedical Materials Research Part A (2011) 97A:74-84.

Svensson L, Artursson K, Berg C, Nicholls IA. Infection Ecology and Epidemiology, IEE Network - A New Interdisciplinary Collaboration of Researchers in Zoonotic Infections. EcoHealth (2011) 7:S80-S81.

Nicholls IA, Shoravi S, Orozovic K, Olsson GD, Karlsson BCG. Synthetic Neuraminidases: Nanostructured Materials for Environmental Monitoring. EcoHealth (2011) 7:S97-S97.

2010

Karlsson BCG, Rosengren AM, Näslund I, Andersson PO, Nicholls IA. Synthetic Human Albumin Sudlow I Binding Site Mimics. (2010) Journal of Medicinal Chemistry (2010) 53:7932-7937

Rosengren, KJ, Craik, DJ. Peptide rope tricks. chimica oggi/Chemistry Today (2010) 28:28-+.

Haugaard-Kedström LM, Hossain MA, Daly NL, Bathgate RAD, Craik DJ, Wade JD, Rosengren KJ. Characterisation of the Human INSL5 Solution Structure. Journal of Peptide Science (2010) 16:154-154.

Nicholls IA, Karlsson BCG, Rosengren, AM, Henschel H. Warfarin: An environment-dependent switchable molecular probe. Journal of Molecular Recognition (2010) 23:604-608

Henschel H, Karlsson BCG, Rosengren, AM, Nicholls IA. The mechanistic basis for warfarin's structural diversity and implications for its bioavailability. Journal of Molecular Structure: THEOCHEM (2010) 958:7-9

Legrand S, Heikkinen H, Nicholls IA, Root A , Svenson J, Unelius CR. Preparation, characterization and application of a stationary chromatographic phase from a new (+)-tartaric acid derivative. Tetrahedron Letters (2010) 51:2258-2261.

Ankarloo J, Wikman S, Nicholls IA. Escherichia coli mar and acrAB Mutants Display No Tolerance to Simple Alcohols. International Journal of Molecular Sciences (2010) 11:1403-1412.

Plan MR, Rosengren, KJ, Sando, L, Daly, NL, Craik, DJ. Structural and Biochemical Characteristics of the Cyclotide Kalata B5 from Oldenlandia affinis. Biopolymers (2010) 94:647-658.

Haugaard-Kedström LM, Hossain MA, Daly NL, Bathgate,RAD, Wade JD, Craik DJ, Rosengren KJ. Structural Characterization of the Relaxin-3IINSL5 Chimera Peptide - A Selective RXFP3 and RXFP4 Agonist. Journal of Peptide Science (2010) 16:39.

Haugaard-Kedström LM, Hossain MA, Daly NL, Bathgate RAD, Craik DJ, Wade JD, Rosengren KJ. Characterisation of the Human INSL5 Solution Structure. Journal of Peptide Science (2010) 16:154.

Bergman IM, Rosengren JK, Edman K, Edfors I. European wild boars and domestic pigs display different polymorphic patterns in the Toll-like receptor (TLR) 1, TLR2, and TLR6 genes. Immunogenetics (2010) 62:49-58.

2009

Rosengren KJ, Craik DJ. How Bugs Make Lassos. Chemistry & Biology (2009) 16:1211-1212.

Nicholls IA, Andersson HS, Chandler C, Henschel H, Karlsson BCG, Karlsson JG, O’Mahony J, Rosengren AM, Rosengren KJ, Wikman S. Theoretical and computational strategies for rational molecularly imprinted polymer design. Biosensors and Bioelectronics (2009) 25:543-552.

Rosengren AM, Golker K, Karlsson JG, Nicholls IA. Dielectric constants are not enough: principal component analysis of the influence of solvent properties on molecularly imprinted polymer–ligand rebinding. Biosensors & Bioelectronics (2009) 25:553-557.

Daly NL, Chen YK, Rosengren KJ, Marx UC, Phillips ML, Waring AJ, Wang W, Lehrer RI, Craik DJ. Retrocyclin-2: a potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif. (2009) In: Peptides for Youth - The Proceedings of the 20th American Peptide Symposium, 611:577-578, DelValle S, Escher E, Lubell WD (eds).

Haugaard-Jönsson LM, Hossain MA, Daly NL, Craik DJ, Wade JD, Rosengren KJ. Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework. Biochemical Journal (2009) 419:619-627.

Karlsson BCG, O’Mahony J, Karlsson JG, Bengtsson H, Eriksson LA, Nicholls IA. Structure and Dynamics of Monomer-Template Complexation: An Explanation for Molecularly Imprinted Polymer Recognition Site Heterogeneity. Journal of the American Chemical Society (2009) 131:13297-13304.

Daly NL, Rosengren KJ, Craik DJ. Discovery, structure and biological activities of cyclotides. Advanced Drug Delivery Reviews (2009) 61:918-930.

Rosengren-Holmberg JP, Karlsson JG, Svenson J, Andersson HS, Nicholls IA. Synthesis and ligand recognition of paracetamol selective polymers: semi-covalent versus non-covalent molecular imprinting. Organic & Biomolecular Chemistry (2009) 7:3148-3155.

Göransson U, Herrmann A, Burman R, Haugaard-Jonsson LM, Rosengren KJ. The Conserved Glu in the Cyclotide Cycloviolacin O2 Has a Key Structural Role. Chembiochem (2009) 10:2354-2360.

Karlsson BCG, Rosengren AM, Andersson PO, Nicholls IA. Molecular insights on the two fluorescence lifetimes displayed by warfarin from fluorescence anisotropy and molecular dynamics studies. Journal of Physical Chemistry B (2009) 113:7945-7949.

Hossain MA, Rosengren KJ, Zhang SD, Bathgate RAD, Tregear GW, van Lierop BJ, Robinson AJ, Wade JD. Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity. Organic & Biomolecular Chemistry (2009) 7:1547-1553.

Wang CK, Hu SH, Martin JL, Sjogren T, Hajdu J, Bohlin L, Claeson P, Göransson U, Rosengren KJ, Tang J, Tan NH, Craik, DJ. Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold. Journal of Biological Chemistry (2009) 284:10672-10683.

Hossain MA, Bathgate RAD, Rosengren KJ, Shabanpoor F, Zhang SD, Lin F, Tregear GW, Wade JD. The Structural and Functional Role of the B-chain C-terminal Arginine in the Relaxin-3 Peptide Antagonist, R3(BD23-27)R/I5. Chemical Biology & Drug Design (2009) 73:46-52.

Kirsch N, Hedin-Dahlström J, Henschel H, Whitcombe MJ, Wikman S, Nicholls IA. Molecularly Imprinted Polymer Catalysis of a Diels-Alder Reaction. Journal of Molecular Catalysis B: Enzymatic (2009) 58:110-117.

Haugaard-Jönsson LM, Hossain MA, Daly NL, Bathgate RAD, Wade JD, Craik DJ, Rosengren KJ. Structural Properties of Relaxin Chimeras: NMR Characterization of the R3/I5 Relaxin Peptide. Annals of the New York Academy of Sciences (2009) 1160:27-30.

Rosengren KJ, Bathgate RAD, Craik DJ, Daly NL, Haugaard-Jönsson LM, Hossain MA, Wade JD. Structural insights into the function of relaxins. Annals of the New York Academy of Sciences (2009) 1160:20-26.

Petcu M, Karlsson JG, Whitcombe MJ, Nicholls IA. Probing the limits of molecular imprinting: strategies with a template of limited size and functionality. Journal of Molecular Recognition (2009) 22:18-25.