Bioorganic and Biophysical Chemistry Laboratory

The Bioorganic and Biophysical Chemistry Laboratory (BBCL) is based in Kalmar at the Faculty of Health and Life Sciences. As the name suggests, we are a multidisciplinary chemical sciences research team, with focus on the study of both organic chemistry and physical chemistry and their application to problems of more biological significance.

Our research

The research activities of the Bioorganic and Biophysical Chemistry Laboratory fall into the following areas:

  1. The design, synthesis and evaluation of novel synthetic recognition systems. The study of molecular imprinting is an important aspect of our work in this area and the knowledge gained is being used for the development of mimics of enzymes and antibodies for applications in synthetic organic chemistry, biotechnology and clinical research.
  2. Fundamental studies in molecular recognition involving the thermodynamic characterisation of ligand - receptor binding events.
  3. The application of combinatorial chemistry and biology to the identification of new recognition elements.
  4. The study of microbiological and biomacromolecular stability and viability in chemically and physically extreme environments.
  5. Bionanotechnology: molecular motors. The study and application of motor protein function on micro and nano-scales.
  6. The development and use of spectroscopic methods for the study of synthetic and biological recognition systems.

Modern laboratories

Our research is performed in modern laboratories and we are equipped with, or have direct access to:

  • Spectroscopy: NMR (500 MHz, Varian), fluorescence (3 instruments, including TIRF and stop-flow), UV, FT-IR, MS (MALDI-TOF)
  • Molecular modelling: 32 core cluster with software for molecular dynamics (Amber, ver. 10, Gromacs, ver. 4.0), DFT (Siesta, ver. 2.0.2) and visualisation (VMD, ver. 1.8.6, Molekel, ver. 4.3)
  • Microscopy: SEM, confocal fluorescence, AFM (nQuip), FT-IR
  • Chromatography: HPLC (several), LC-MS, GC-MS, CE/CEC, FPLC
  • Sensor platforms: SPR (Biacore X), QCM (Attana Cell-200, Attana-100, Attana-80)
  • Miscellaneous: Isotope labs & scintillation counting, cell and virus culture labs, cell counter, flow cytometry, goniometry, viscosometry, dielectric constant meter

Granting agencies and industrial partners

Our research is run with the support of a number of granting agencies and industrial partners:

The BBCL research group is part of the Department of Chemistry and Biomedical Sciences and the Linnæus University Centre of Excellence (LNUC) for Biomaterials Chemistry.

Teaching

The majority of the people in BBCL contribute to the teaching activities at the Faculty of Health and Life Sciences. Members of the group have significant involvement in the teaching of undergraduate courses in:

  • General Chemistry
  • Inorganic Chemistry
  • Organic Chemistry
  • Physical Chemistry
  • Analytical Chemistry
  • Medicinal Chemistry
  • Bioorganic Chemistry
  • Laboratory methodology
  • Nutrition

These courses are integral components of a number of degree programmes:

  • Biology
  • Biomedical Chemistry
  • Biomedical Laboratory Science
  • Engineering
  • Environmental Management
  • Nanoscience
  • Nutrition and Food Science
  • Optometry
  • Pharmacy
  • Teacher Education.

In addition, members of the team contribute to a range of PhD courses offered by the faculty.

Seminars

Welcome to our seminars that take place Fridays at 2:30-3:30 in room N218 and are in English, unless otherwise stated.

Spring 2016

Jan 22 MSc & BSc examination project presentations & MSc half-time reports
Jan 29 MSc & BSc examination project presentations & MSc half-time reports

Feb 5 Subban Kathirivan*
Feb 12 No seminar
Feb 19 Gustaf Olsson*
Feb 26 Maria Canterella, University of Catania, Italy*

March 4 Antoine Buetti-Dinh*
March 11 Kristina Magnusson
March 18 Kerstin Golker*
March 25 Easter

April 1 Research Council application writing
April 8 Natacha Ndizeye*
April 15 Swapnil Chavan* – thesis defence (preliminary)
April 22 Bengt Persson*
April 29 Helena Vandesande

May 6 Squeeze day holiday
May 13 Alf Månsson
May 19 Peter Lewis – thesis defence (preliminary)
May 20 Akademisk högtid
May 27 Daniel Fernando – thesis defence (preliminary)
May 31-June 3 BSc & MSc examination project presentations & graduation ceremony

June 10 LNUC–BMC workshop open lectures – to be announced
June 17 Xiaofen Wu – thesis defence (preliminary)

Lecture titles should be posted by the presenter (or their host) on the staff room information board.

* = LNUC–BMC colloquium

Publications

Staff

News

MSc student [January, 2016]
Shangquin Zhao, joined us to undertake his MSc thesis studies.

Visiting students [January 25, 2016]
Maria Canterella, University of Catania, Italy, joined us as a as part of the 7th Framework and ERASMUS programs. Alina Sklad, University of Saskatchewan, Canada, joined us for a half year long secondment.

Contact and visiting information

Postal address

Bioorganic and Biophysical Chemistry Laboratory
Linnaeus University Centre for Biomaterials Chemistry
Department of Chemistry and Biomedical Sciences
Linnaeus University
SE-391 82 Kalmar
Sweden

Visiting address

Norra vägen 49, Kalmar
Fax: +46 (0)480–44 62 44
Phone: +46 (0)480–44 62 00 (operator)

Getting here

By car: E22 from Copenhagen/Malmö/Lund, or E4 then E22 from Stockholm.
By train: Regular train services to/from Copenhagen Airport/Malmö/Lund, Gothenburg and Stockholm. We are located 1 km from the Central Station.
By air: Several flights to and from Stockholm each day with either SAS (Arlanda) or Kalmarflyg (Bromma). The airport is a 10 min drive from the Department.