Camilla Mohlin
Assistant Professor
Department of Chemistry and Biomedical Sciences
Faculty of Health and Life Sciences
My ongoing research projects
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Project: Advanced Materials for Personalized Medicine & Diagnostics (AMPMeD) This project seeks to develop highly sensitive and robust diagnostic platforms and accommodating sampling technologies for…
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Project: Chronic inflammation in patients treated for neovascular age-related macular degeneration - investigating new treatment pathways Age-related macular degeneration (AMD) is an irreversible eye…
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Project: Do complement regulators control the pathophysiology of macular degeneration? The research project aims to investigate the effect of complement system regulators, mainly factor H, on the…
Publications
Article in journal (Refereed)
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Andersson, L., Sjöström, D.J., Quach, H.Q., Hägerström, K., Hurler, L., et al. (2024). Storage of Transfusion Platelet Concentrates is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor. International Journal of Molecular Sciences. 25 (2).
Status: Published -
Sjöström, D.J., Grill, B., Ambrosetti, E., Veetil, A.A., Mohlin, C., et al. (2023). Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding. Journal of Molecular Biology. 435 (20).
Status: Published -
Gerogianni, A., Bal, M., Mohlin, C., Woodruff, T.M., Lambris, J.D., et al. (2023). In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model. Frontiers in Immunology. 14.
Status: Published -
Johansson, K., Mohlin, C. (2023). Microglia in Cultured Porcine Retina : Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International Journal of Molecular Sciences. 24 (1).
Status: Published -
Gerogianni, A., Dimitrov, J.D., Zarantonello, A., Poillerat, V., Chonat, S., et al. (2022). Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation. Frontiers in Immunology. 13.
Status: Published -
Sjöström, D.J., Mohlin, C., Ambrosetti, E., Garforth, S.J., Teixeira, A.I., et al. (2022). Motif-driven protein binder design towards transferrin receptor helical domain. The FEBS Journal. 289 (10). 2935-2947.
Status: Published -
Islam, R., Islam, M.M., Nilsson, P.H., Mohlin, C., Hagen, K.T., et al. (2021). Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia. 127. 169-179.
Status: Published -
Johansson, K., Svensson, L.A., Mohlin, C. (2020). Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro : Presumptive dark microglia in porcine retina. Experimental Eye Research. 200. 1-10.
Status: Published -
Nilsson Ekdahl, K., Mohlin, C., Adler, A., Aman, A., Manivel, V.A., et al. (2019). Is generation of C-3(H2O) necessary for activation of the alternative pathway in real life?. Molecular Immunology. 114. 353-361.
Status: Published -
Mohlin, C., Sandholm, K., Kvanta, A., Nilsson Ekdahl, K., Johansson, K. (2018). A model to study complement involvement in experimental retinal degeneration.. Upsala Journal of Medical Sciences. 123 (1). 28-42.
Status: Published -
Mohlin, C., Delbro, D., Kvanta, A., Johansson, K. (2018). Evaluation of Congo Red Staining in Degenerating Porcine Photoreceptors In Vitro : Protective Effects by Structural and Trophic Support. Journal of Histochemistry and Cytochemistry. 66 (9).
Status: Published -
Nilsson Ekdahl, K., Davoodpour, P., Ekstrand-Hammarström, B., Fromell, K., Hamad, O.A., et al. (2018). Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles. Nanomedicine : Nanotechnology, Biology and Medicine. 14 (3). 735-744.
Status: Published -
Mollick, T., Mohlin, C., Johansson, K. (2016). Human neural progenitor cells decrease photoreceptor degeneration, normalize opsin distribution and support synapse structure in cultured porcine retina. Brain Research. 1646. 522-534.
Status: Published -
Mohlin, C., Taylor, L., Ghosh, F., Johansson, K. (2014). Autophagy and ER-stress contribute to photoreceptor degeneration in cultured adult porcine retina. Brain Research. 1585. 167-183.
Status: Published -
Demirel, I., Vumma, R., Mohlin, C., Svensson, L., Säve, S., et al. (2012). Nitric Oxide Activates IL-6 Production and Expression in Human Renal Epithelial Cells. American Journal of Nephrology. 36 (6). 524-530.
Status: Published -
Säve, S., Mohlin, C., Vumma, R., Persson, K. (2011). Activation of Adenosine A(2A) Receptors Inhibits Neutrophil Transuroepithelial Migration. Infection and Immunity. 79 (8). 3431-3437.
Status: Published -
Mohlin, C., Johansson, K. (2011). Death of photoreceptors in organotypic retinal explant cultures: implication of rhodopsin accumulation and endoplasmic reticulum stress.. Journal of Neuroscience Methods. 197 (1). 56-64.
Status: Published -
Mohlin, C., Liljekvist-Soltic, I., Johansson, K. (2011). Further assessment of neuropathology in retinal explants and neuroprotection by human neural progenitor cells.. Journal of Neural Engineering. 8 (6).
Status: Published -
Englund Johansson, U., Mohlin, C., Liljekvist-Soltic, I., Ekström, P., Johansson, K. (2010). Human neural progenitor cells promote photoreceptor survival in retinal explants. Experimental Eye Research. 90 (2). 292-299.
Status: Published -
Gullberg, M., Tolf, C., Jonsson, N., Polacek, C., Precechtelova, J., et al. (2010). A single coxsackievirus B2 capsid residue controls cytolysis and apoptosis in rhabdomyosarcoma cells.. Journal of Virology. 84 (12). 5868-5879.
Status: Published -
Svensson, L., Mohlin, C., Persson, K. (2009). Upregulation of Heme Oxygenase-1 as a Host Mechanism for Protection Against Nitric Oxide–induced Damage in Human Renal Epithelial Cells. Urology. 73 (5). 749-753.
Status: Published -
Säve, S., Mjösberg, J., Poljakovic, M., Mohlin, C., Persson, K. (2009). Adenosine receptor expression in Escherichia coli-infected and cytokine-stimulated human urinary tract epithelial cells. BJU International. 104 (11). 1758-1765.
Status: Published -
Mohlin, C., Säve, S., Nilsson, M., Persson, K. (2009). Studies of the Extracellular ATP-Adenosine Pathway in Human Urinary Tract Epithelial Cells. Pharmacology. 84 (4). 196-202.
Status: Published
Conference paper (Refereed)
- Baskaran, K., Nilsson, I., Ringbäck, K., Ternehäll, M., Svanfeldt, C., et al. (2024). Swedish version of the Massof activity inventory to measure vision-related activity difficulties among patients with nAMD. Acta Ophthalmol, vol 102, issue S279: Special Issue:Abstracts from the 2023 European Association for Vision and Eye Research Festival, 26‐28 October 2023, Valencia.
- Mohlin, C. (2016). Evaluation of Congo red fluorescence in degenerating cultured porcine retina.. .
- Mohlin, C., Mollik, T., Johansson, K. (2014). Human neural progenitor cells are not sufficient to support degenerating photoreceptors in cultured porcine retina.. .
Chapter in book (Refereed)
- Sandholm, K., Persson, B., Abdalla, S., Mohlin, C., Nilsson, B., et al. (2021). Quantification of Complement Proteins with Special Reference to C1q : Multiplex Versus ELISA Versus Rocket Immunoelectrophoresis Versus Nephelometry. The Complement System : Methods in Molecular Biology. Humana Press. 33-41.
- Mohlin, C., Liljekvist-Soltic, I., Olofsson, J., Johansson, K. (2011). Neuropathology of cultured retinas : degenerative events and rescue paradigms. Advances in Eye Research. Volume 2. Nova Science Publishers, Inc.. 177-190.
Article, review/survey (Refereed)
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Nilsson Ekdahl, K., Fromell, K., Mohlin, C., Teramura, Y., Nilsson, B. (2019). A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity. Science and Technology of Advanced Materials. Taylor & Francis Group. 20 (1). 688-698.
Status: Published -
Mohebnasab, M., Eriksson, O., Persson, B., Sandholm, K., Mohlin, C., et al. (2019). Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics. Frontiers in Immunology. Frontiers Media S.A.. 10. 1-13.
Status: Published -
Eriksson, O., Mohlin, C., Nilsson, B., Nilsson Ekdahl, K. (2019). The Human Platelet as an Innate Immune Cell : Interactions Between Activated Platelets and the Complement System. Frontiers in Immunology. Frontiers Media S.A.. 10. 1-16.
Status: Published -
Biglarnia, A., Huber-Lang, M., Mohlin, C., Nilsson Ekdahl, K., Nilsson, B. (2018). The multifaceted role of complement in kidney transplantation. Nature Reviews Nephrology. Nature Publishing Group. 14 (12). 767-781.
Status: Published -
Nilsson Ekdahl, K., Persson, B., Mohlin, C., Sandholm, K., Skattum, L., et al. (2018). Interpretation of Serological Complement Biomarkers in Disease. Frontiers in Immunology. Frontiers Media S.A.. 9.
Status: Published -
Mohlin, C., Sandholm, K., Nilsson Ekdahl, K., Nilsson, B. (2017). The link between morphology and complement in ocular disease. Molecular Immunology. Elsevier. 89. 84-99.
Status: Published
Article in journal (Other academic)
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Mohlin, C., Petrus-Reurer, S., Lanner, F., Sandholm, K., Nilsson, P.H., et al. (2018). Is the polarized secretion of complement factor H of importance in age-related macular degeneration?. Investigative Ophthalmology and Visual Science. 59 (9).
Status: Published -
Mohlin, C., Petrus-Reurer, S., Lanner, F., Sandholm, K., Kvanta, A., et al. (2017). Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina. Molecular Immunology. 89. 162-163.
Status: Published -
Mohlin, C., Johansson, K., Nilsson Ekdahl, K. (2015). Complement factor involvement during experimental AMD. Molecular Immunology. 67 (1). 163-163.
Status: Published
Doctoral thesis, comprehensive summary (Other academic)
- Mohlin, C. (2013). Neural progenitor cell-derived neurotrophic support for the degenerating retina : an in vitro study. Doctoral Thesis. Växjö, Linnaeus University press. 77.
Manuscript (preprint) (Other academic)
- Gerogianni, A., Sørensen, G., Nilsen Hoel, T., Mcadam, K.E., Ludviksen, J.A., et al. Implantation of a continuous-flow left ventricular assist device is associated with a significant but transient acute thromboinflammatory response.
- Säve, S., Mohlin, C., Vumma, R., Persson, K. Activation of adenosine A2A receptors inhibit neutrophil transuroepithelial migration.
- Mohlin, C., Taylor, L., Ghosh, F., Johansson, K. Autophagy en ER-stress contribute to photoreceptor degenenration in cultured adult porcine retina.