Camilla Mohlin
Assistant Professor
Department of Chemistry and Biomedical Sciences
Faculty of Health and Life Sciences
My ongoing research projects
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Project: Advanced Materials for Personalized Medicine & Diagnostics (AMPMeD) This project seeks to develop highly sensitive and robust diagnostic platforms and accommodating sampling technologies for…
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Project: Chronic inflammation in patients treated for neovascular age-related macular degeneration - investigating new treatment pathways Age-related macular degeneration (AMD) is an irreversible eye…
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Project: Do complement regulators control the pathophysiology of macular degeneration? The research project aims to investigate the effect of complement system regulators, mainly factor H, on the…
Publications
Article in journal (Refereed)
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Eikrem, D., Manivel, V.A., Whittaker, J., Hamad, O.A., Mohlin, C., et al. (2025). Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes. Frontiers in Immunology. 16.
Status: Published -
Veetil, A.A., Sjöström, D.J., Iribarren, C., Mohlin, C., Ambrosetti, E., et al. (2025). Targeting the apical domain of the transferrin receptor : Development of a new protein scaffold for cellular delivery. Protein Science. 34 (12).
Status: Published -
Nilsson, I., Senra, H., Baskaran, K., Mohlin, C., Macedo, A.F. (2025). Perceived stress levels among patients treated for neovascular age-related macular degeneration with anti-VEGF injections. Graefe's Archives for Clinical and Experimental Ophthalmology. 263. 2523-2531.
Status: Published -
Johansson, K., Mohlin, C. (2024). Qualitative evaluations of reactive microglial heterogeneity in cultured porcine retina. Histology and Histopathology. 39 (12). 1611-1620.
Status: Published -
Andersson, L., Sjöström, D.J., Quach, H.Q., Hägerström, K., Hurler, L., et al. (2024). Storage of Transfusion Platelet Concentrates is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor. International Journal of Molecular Sciences. 25 (2).
Status: Published -
Sjöström, D.J., Grill, B., Ambrosetti, E., Veetil, A.A., Mohlin, C., et al. (2023). Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding. Journal of Molecular Biology. 435 (20).
Status: Published -
Johansson, K., Mohlin, C. (2023). Microglia in Cultured Porcine Retina : Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International Journal of Molecular Sciences. 24 (1).
Status: Published -
Gerogianni, A., Bal, M., Mohlin, C., Woodruff, T.M., Lambris, J.D., et al. (2023). In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model. Frontiers in Immunology. 14.
Status: Published -
Gerogianni, A., Dimitrov, J.D., Zarantonello, A., Poillerat, V., Chonat, S., et al. (2022). Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation. Frontiers in Immunology. 13.
Status: Published -
Sjöström, D.J., Mohlin, C., Ambrosetti, E., Garforth, S.J., Teixeira, A.I., et al. (2022). Motif-driven protein binder design towards transferrin receptor helical domain. The FEBS Journal. 289 (10). 2935-2947.
Status: Published -
Islam, R., Islam, M.M., Nilsson, P.H., Mohlin, C., Hagen, K.T., et al. (2021). Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia. 127. 169-179.
Status: Published -
Johansson, K., Svensson, L.A., Mohlin, C. (2020). Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro : Presumptive dark microglia in porcine retina. Experimental Eye Research. 200. 1-10.
Status: Published -
Nilsson Ekdahl, K., Mohlin, C., Adler, A., Aman, A., Manivel, V.A., et al. (2019). Is generation of C-3(H2O) necessary for activation of the alternative pathway in real life?. Molecular Immunology. 114. 353-361.
Status: Published -
Mohlin, C., Sandholm, K., Kvanta, A., Nilsson Ekdahl, K., Johansson, K. (2018). A model to study complement involvement in experimental retinal degeneration.. Upsala Journal of Medical Sciences. 123 (1). 28-42.
Status: Published -
Nilsson Ekdahl, K., Davoodpour, P., Ekstrand-Hammarström, B., Fromell, K., Hamad, O.A., et al. (2018). Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles. Nanomedicine : Nanotechnology, Biology and Medicine. 14 (3). 735-744.
Status: Published -
Mohlin, C., Delbro, D., Kvanta, A., Johansson, K. (2018). Evaluation of Congo Red Staining in Degenerating Porcine Photoreceptors In Vitro : Protective Effects by Structural and Trophic Support. Journal of Histochemistry and Cytochemistry. 66 (9).
Status: Published -
Mollick, T., Mohlin, C., Johansson, K. (2016). Human neural progenitor cells decrease photoreceptor degeneration, normalize opsin distribution and support synapse structure in cultured porcine retina. Brain Research. 1646. 522-534.
Status: Published -
Mohlin, C., Taylor, L., Ghosh, F., Johansson, K. (2014). Autophagy and ER-stress contribute to photoreceptor degeneration in cultured adult porcine retina. Brain Research. 1585. 167-183.
Status: Published -
Demirel, I., Vumma, R., Mohlin, C., Svensson, L., Säve, S., et al. (2012). Nitric Oxide Activates IL-6 Production and Expression in Human Renal Epithelial Cells. American Journal of Nephrology. 36 (6). 524-530.
Status: Published -
Säve, S., Mohlin, C., Vumma, R., Persson, K. (2011). Activation of Adenosine A(2A) Receptors Inhibits Neutrophil Transuroepithelial Migration. Infection and Immunity. 79 (8). 3431-3437.
Status: Published -
Mohlin, C., Johansson, K. (2011). Death of photoreceptors in organotypic retinal explant cultures: implication of rhodopsin accumulation and endoplasmic reticulum stress.. Journal of Neuroscience Methods. 197 (1). 56-64.
Status: Published -
Mohlin, C., Liljekvist-Soltic, I., Johansson, K. (2011). Further assessment of neuropathology in retinal explants and neuroprotection by human neural progenitor cells.. Journal of Neural Engineering. 8 (6).
Status: Published -
Englund Johansson, U., Mohlin, C., Liljekvist-Soltic, I., Ekström, P., Johansson, K. (2010). Human neural progenitor cells promote photoreceptor survival in retinal explants. Experimental Eye Research. 90 (2). 292-299.
Status: Published -
Gullberg, M., Tolf, C., Jonsson, N., Polacek, C., Precechtelova, J., et al. (2010). A single coxsackievirus B2 capsid residue controls cytolysis and apoptosis in rhabdomyosarcoma cells.. Journal of Virology. 84 (12). 5868-5879.
Status: Published -
Svensson, L., Mohlin, C., Persson, K. (2009). Upregulation of Heme Oxygenase-1 as a Host Mechanism for Protection Against Nitric Oxide–induced Damage in Human Renal Epithelial Cells. Urology. 73 (5). 749-753.
Status: Published -
Säve, S., Mjösberg, J., Poljakovic, M., Mohlin, C., Persson, K. (2009). Adenosine receptor expression in Escherichia coli-infected and cytokine-stimulated human urinary tract epithelial cells. BJU International. 104 (11). 1758-1765.
Status: Published -
Mohlin, C., Säve, S., Nilsson, M., Persson, K. (2009). Studies of the Extracellular ATP-Adenosine Pathway in Human Urinary Tract Epithelial Cells. Pharmacology. 84 (4). 196-202.
Status: Published
Conference paper (Refereed)
- Nilsson, I., Senra, H., Baskaran, K., Mohlin, C., Macedo, A.F. (2025). Is perceived social support relevant for depression and anxiety in patients with age-related neovascular macular degeneration?. ISLRR 2025 Abstract Book. 189.
- Macedo, A.F., Nilsson, I., Baskaran, K., De Zanet, S., Apostolopoulos, S., et al. (2025). Prediction of success and failure events during the journey of neovascular AMD treatments with anti-VEGF injections : a preliminary analysis. ARVO Annual Meeting Abstracts. 1862.
- Baskaran, K., Nilsson, I., Ringbäck, K., Ternehäll, M., Svanfeldt, C., et al. (2024). Swedish version of the Massof activity inventory to measure vision-related activity difficulties among patients with nAMD. Acta Ophthalmol, vol 102, issue S279: Special Issue:Abstracts from the 2023 European Association for Vision and Eye Research Festival, 26‐28 October 2023, Valencia.
- Macedo, A.F., Nilsson, I., Svanfeldt, C., Mohlin, C., Baskaran, K. (2024). Rasch analysis of an activity inventory to measure vision-related activity difficulties : a neovascular AMD specific study. . 28.
- Mohlin, C. (2016). Evaluation of Congo red fluorescence in degenerating cultured porcine retina.. .
- Mohlin, C., Mollik, T., Johansson, K. (2014). Human neural progenitor cells are not sufficient to support degenerating photoreceptors in cultured porcine retina.. .
Chapter in book (Refereed)
- Sandholm, K., Persson, B., Abdalla, S., Mohlin, C., Nilsson, B., et al. (2021). Quantification of Complement Proteins with Special Reference to C1q : Multiplex Versus ELISA Versus Rocket Immunoelectrophoresis Versus Nephelometry. The Complement System : Methods in Molecular Biology. Humana Press. 33-41.
- Mohlin, C., Liljekvist-Soltic, I., Olofsson, J., Johansson, K. (2011). Neuropathology of cultured retinas : degenerative events and rescue paradigms. Advances in Eye Research. Volume 2. Nova Science Publishers, Inc.. 177-190.
Article, review/survey (Refereed)
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Nilsson Ekdahl, K., Fromell, K., Mohlin, C., Teramura, Y., Nilsson, B. (2019). A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity. Science and Technology of Advanced Materials. Taylor & Francis Group. 20 (1). 688-698.
Status: Published -
Mohebnasab, M., Eriksson, O., Persson, B., Sandholm, K., Mohlin, C., et al. (2019). Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics. Frontiers in Immunology. Frontiers Media S.A.. 10. 1-13.
Status: Published -
Eriksson, O., Mohlin, C., Nilsson, B., Nilsson Ekdahl, K. (2019). The Human Platelet as an Innate Immune Cell : Interactions Between Activated Platelets and the Complement System. Frontiers in Immunology. Frontiers Media S.A.. 10. 1-16.
Status: Published -
Nilsson Ekdahl, K., Persson, B., Mohlin, C., Sandholm, K., Skattum, L., et al. (2018). Interpretation of Serological Complement Biomarkers in Disease. Frontiers in Immunology. Frontiers Media S.A.. 9.
Status: Published -
Biglarnia, A., Huber-Lang, M., Mohlin, C., Nilsson Ekdahl, K., Nilsson, B. (2018). The multifaceted role of complement in kidney transplantation. Nature Reviews Nephrology. Nature Publishing Group. 14 (12). 767-781.
Status: Published -
Mohlin, C., Sandholm, K., Nilsson Ekdahl, K., Nilsson, B. (2017). The link between morphology and complement in ocular disease. Molecular Immunology. Elsevier. 89. 84-99.
Status: Published
Article in journal (Other academic)
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Macedo, A.F., Nilsson, I., Svanfeldt, C., Melin, J., Mohlin, C., et al. (2024). Vision-related activity difficulties in people diagnosed with neovascular age-related macular degeneration and with vision impairment. Investigative Ophthalmology and Visual Science. 65 (7). 443-443.
Status: Published -
Macedo, A.F., Nilsson, I., Ask, S., Bartoszek, J., Khudair, R., et al. (2023). Investigating plasma chemokines in patients diagnosed with neovascular age-related macular degeneration treated with anti-VEGF injections. Investigative Ophthalmology and Visual Science. 64 (8). 2226-2226.
Status: Published -
Nilsson, I., Ask, S., Nilsson, P.H., Mohlin, C., Hugo, S., et al. (2023). Perceived stress levels in patients diagnosed with and treated for neovascular age-related macular degeneration with anti-vascular endothelial growth factors. Investigative Ophthalmology and Visual Science. 64 (8). 2225-2225.
Status: Published -
Mohlin, C., Petrus-Reurer, S., Lanner, F., Sandholm, K., Nilsson, P.H., et al. (2018). Is the polarized secretion of complement factor H of importance in age-related macular degeneration?. Investigative Ophthalmology and Visual Science. 59 (9).
Status: Published -
Mohlin, C., Petrus-Reurer, S., Lanner, F., Sandholm, K., Kvanta, A., et al. (2017). Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina. Molecular Immunology. 89. 162-163.
Status: Published -
Mohlin, C., Johansson, K., Nilsson Ekdahl, K. (2015). Complement factor involvement during experimental AMD. Molecular Immunology. 67 (1). 163-163.
Status: Published
Conference paper (Other academic)
- Nilsson, I., Hernández-Moreno, L., Baskaran, K., Mohlin, C., Senra, H., et al. (2024). Cultural differences in perceived social support in patients with retinal diseases. Abstracts from the 2023 European Association for Vision and Eye Research Festival, 26–28 October 2023, Valencia.
Doctoral thesis, comprehensive summary (Other academic)
- Mohlin, C. (2013). Neural progenitor cell-derived neurotrophic support for the degenerating retina : an in vitro study. Doctoral Thesis. Växjö, Linnaeus University press. 77.
Manuscript (preprint) (Other academic)
- Gerogianni, A., Sørensen, G., Nilsen Hoel, T., Mcadam, K.E., Ludviksen, J.A., et al. Implantation of a continuous-flow left ventricular assist device is associated with a significant but transient acute thromboinflammatory response.
- Säve, S., Mohlin, C., Vumma, R., Persson, K. Activation of adenosine A2A receptors inhibit neutrophil transuroepithelial migration.
- Mohlin, C., Taylor, L., Ghosh, F., Johansson, K. Autophagy en ER-stress contribute to photoreceptor degenenration in cultured adult porcine retina.