Maria Bergström

Senior lecturer

Department of Chemistry and Biomedical Sciences Faculty of Health and Life Sciences

maria.bergstrom@lnu.se

+46 480-44 67 41

+46 73-092 57 65

I am a senior lecturer in biochemical methodology and conducts research in collaboration with Prof Cornelia Witthöft (Food Science). I have a chemistry degree from Stockholm University and a background in the pharmaceutical industry (Astra, Kabi, SBL) and a broad chemical competence. I am particularly interested in instrumental methods such as mass spectrometry, gas chromatography and liquid chromatography.

Teaching

I am the program coordinator of the bachelor program Nutrition and Food Sciences (NutriLivs), and teaches general chemistry, biochemistry, food chemistry and analytical chemistry. I also supervise Degree Projects work on the BMA program and NutriLivs program and I am course coordinator/examiner for the Degree Project in Chemistry at first level (15 ECTS credits), and a number of other courses.

Research

I am a member of the Food Science Research Group led by Cornelia Witthöft. I am also associated with the research groups "Ecological Chemistry" led by Prof Rikard Unelius. My current research is focused on developing analyzes for micronutrients and phytochemicals, and how their content can be optimized in food.

Commissions

Member of the bord of Saco and Sulf at Lnu. I am the head of the local Sulf union at Linnaeus University.

My research groups

My completed research projects

Publications

Article in journal (Refereed)

Liu, J., Hefni, M.E., Witthöft, C.M., Bergström, M., Burleigh, S., et al. (2022). Effects of Whole Brown Bean and Its Isolated Fiber Fraction on Plasma Lipid Profile, Atherosclerosis, Gut Microbiota, and Microbiota-Dependent Metabolites in Apoe−/− Mice. Nutrients. 14 (5).
Status: Published
Liu, J., Hefni, M.E., Witthöft, C.M., Bergström, M., Burleigh, S., et al. (2022). On the effect of flavonoids and dietary fibre in lingonberries on atherosclerotic plaques, lipid profiles and gut microbiota composition in Apoe(-/-) mice. International Journal of Food Sciences and Nutrition. 73 (8). 1080-1090.
Status: Published
Hefni, M.E., Bergström, M., Lennqvist, T., Fagerström, C., Witthöft, C.M. (2021). Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS. Analytical and Bioanalytical Chemistry. 413. 5349-5360.
Status: Published
Bergström, M., Håkansson, A., Blücher, A., Andersson, H.S. (2020). From carbohydrates to fat : Trends in food intake among Swedish nutrition students from 2002 to 2017. PLOS ONE. 15 (1). 1-14.
Status: Published
Monaco, S., Walpole, S., Doukani, H., Nepravishta, R., Martnezbailn, M., et al. (2020). Exploring Multi-Subsite Binding Pockets in Proteins : DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B. Chemistry - A European Journal. 26 (44). 10024-10034.
Status: Published
Ferawati, F., Witthöft, C.M., Bergström, M. (2020). Characterization of volatile compounds in Swedish yellow and gray peas : implications for new legume‐based ingredients. Legume Science. 2 (4).
Status: Published
Bergström, M., Ganji, S., Naidu Veluru, R., Unelius, C.R. (2017). N-Iodosuccinimide (NIS) in Direct Aromatic Iodination. European Journal of Organic Chemistry. (22). 3234-3239.
Status: Published
Duong-Thi, M., Bergström, M., Edwards, K., Eriksson, J., Ohlson, S., et al. (2016). Lipodisks integrated with weak affinity chromatography enable fragment screening of integral membrane proteins. The Analyst. 141 (3). 981-988.
Status: Published
Duong-Thi, M., Bergström, G., Mandenius, C., Bergström, M., Fex, T., et al. (2014). Comparison of weak affinity chromatography and surface plasmon resonance in determining affinity of small molecules. Analytical Biochemistry. 461. 57-59.
Status: Published
Duong-Thi, M., Bergström, M., Fex, T., Isaksson, R., Ohlson, S. (2013). High-Throughput Fragment Screening by Affinity LC-MS. Journal of Biomolecular Screening. 18 (2). 160-171.
Status: Published
Duong-Thi, M., Bergström, M., Fex, T., Svensson, S., Ohlson, S., et al. (2013). Weak Affinity Chromatography for Evaluation of Stereoisomers in Early Drug Discovery. Journal of Biomolecular Screening. 18 (6). 748-755.
Status: Published
Landström, J., Bergström, M., Hamark, C., Ohlson, S., Widmalm, G. (2012). Combining weak affinity chromatography, NMR spectroscopy and molecular simulations in carbohydrate-lysozyme interaction studies.. Organic and biomolecular chemistry. 10 (15). 3019-3032.
Status: Published
Bergström, M., Åström, E., Påhlsson, P., Ohlson, S. (2012). Elucidating the selectivity of recombinant forms of Aleuria aurantia lectin using weak affinity chromatography. Journal of chromatography. B. 885-886. 66-72.
Status: Published
Duong-Thi, M., Meiby, E., Bergström, M., Fex, T., Isaksson, R., et al. (2011). Weak affinity chromatography as a new approach for fragment screening in drug discovery. Analytical Biochemistry. 414 (1). 138-146.
Status: Published
Cheshev, P., Morelli, L., Marchesi, M., Podlipnik, C., Bergström, M., et al. (2010). Synthesis and affinity evaluation of a small library of bidentate cholera toxin ligands: towards nonhydrolyzable ganglioside mimics. Chemistry - A European Journal. 16 (6). 1951-1967.
Status: Published
Ohlson, S., Duong-Thi, M., Bergström, M., Fex, T., Hansson, L., et al. (2010). Toward high-throughput drug screening on a chip-based parallell affinity separation platform. Journal of Separation Science. 33 (17-18). 2575-2581.
Status: Published
Bergström, M., Liu, S., Kiick, K., Ohlson, S. (2009). Cholera toxin inhibitors studied with High-performance liquid affinity chromatography: arobust method to evaluate receptor-ligand interactions. Chemical Biology and Drug Design. 73 (1). 132-141.
Status: Published
Engström, H., Johansson, R., Koch-Schmidt, P., Gregorius, K., Ohlson, S., et al. (2008). Evaluation of a glucose sensing antibody using weak affinity chromatography. BMC Biomedical chromotography. 22 (3). 272-277.
Status: Published
Nilsson, M., Harang, V., Bergström, M., Ohlson, S., Isaksson, R., et al. (2004). Determination of Protein-Ligand Affinity Constants from Direct Migration Time in Capillary Electrophoresis. Electrophoresis. 25. 1829-1836.
Status: Published
Bergström, M., Nilsson, M., Isaksson, R., Rydén, I., Påhlsson, P., et al. (2004). Lectin Affinity Capillary Electrophoresis in Glycoform Analysis Applying the Partial Filling Technique. Journal of Chromatography B. 809. 323-329.
Status: Published
Bergström, M., Ohlson, S. (2001). Use of perfusive supports in weak affinity chromatography (WAC). Bio-chromatography. 6. 163-172.
Status: Published
Bergström, M., Lundblad, A., Påhlsson, P., Ohlson, S. (1998). Use of weak monoclonal antibodies for affinity chromatography. Journal of Molecular Recognition. 11. 110-113.
Status: Published
Ohlson, S., Bergström, M., Leickt, L., Zopf, D. (1998). Weak affinity chromatography of small saccharides with immobilised wheat germ agglutinin and its application to monitoring of carbohydrate transferase activity. Bioseparation. 7. 101-106.
Status: Published
Leickt, L., Bergström, M., Zopf, D., Ohlson, S. (1997). Bioaffinity chromatography in the 10 mM range of Kd. Analytical biochemistry. 253. 135-136.
Status: Published
Ohlson, S., Bergström, M., Påhlsson, P., Lundblad, A. (1997). Use of monoclonal antibodies for weak affinity chromatography. Journal of Chromatography A. 758. 199-208.
Status: Published

Conference paper (Other academic)

Boman, S., Bergström, M., Blücher, A., Håkansson, A., Andersson, H.S. (2016). Dietary habits of Swedish university students in nutrition science between 2001 and 2016. Abstracts. The 11th NORDIC NUTRITION CONFERENCE NNC2016. “Bridging nutrition sciences for better health in the Nordic countries”.

Doctoral thesis, monograph (Other academic)

Bergström, M. (2006). Analytical affinity separations based on weak protein - carbohydrate interactions. Doctoral Thesis. 129.

Article in journal (Other (popular science, discussion, etc.))

Bergström, M., Andersson, H.S. (2020). Mer fett och minder kolhydrater - trenden fortsätter. Dietisten. (17 April).
Status: Published