Macular degeneration and the role of the complement system

Age-related macular degeneration (AMD) is a leading cause of visual impairment. AMD is characterized by damage to the eye retina and the buildup of subretinal debris i.e. drusen. The complement system has been shown to have an integral role in maintaining of the homeostasis in the ocular environment, however, overactivation can drive ocular diseases.

The development of AMD depends on a complex interplay of risk factors such as age, genetics, and behavior for example diet, smoking, and sunlight etc. Currently, there is no effective curative prevention for the clinical management of AMD. However, the mechanism for complement disease propagation in AMD is not fully understood, although modulation of complement proteins seems to have the potential to become a new therapeutic approach.

In this seminar research fellow Camilla Mohlin gives an overview of AMD that is a progressive neurodegenerative disease with increasing prevalence in the aging population and in need of further investigation and understanding of the disease pathogenesis.

Date: October 18
Time: 13:00-13:40
Location: Room Magenta (Vi2144), Vita, Norra Kajplan 6
The seminar is in English.

Watch the seminar live: https://play.lnu.se/media/t/0_1kowhkux
The seminar will also be available later on LnuPlay.