Anders Götherström: Ancient DNA of disease causing microbes

Välkommen till en föreläsning i Fakulteten för hälso- och livsvetenskaps seminarieserie inom det naturvetenskapliga området.

Bilden föreställer megaliten Gökhem 72. Det äldsta bekräftade resultatet på Yersinia pestis kommer från en liknande megalit, Gökhem 94:1, från ca 5000 år sedan. 

Anders Götherström, professor, Stockholms Universitet


Ancient DNA of disease causing microbes


Ever since ancient DNA was proven to be preserved in prehistoric tissue, collogues have experimented with the possibility of retrieving DNA from disease causing microbes. Especially Mykobacterium tuberculosis was popular in the early days. But only with the introduction of the new sequencing strategies (NGS) was solid and reliable data produced. And NGS related ancient DNA has indeed rewritten the history pathology, just as it has many other fields. The most notorious bacterial caused catastrophe, Yersinia pestis induced plague, seems to have a history in Europe that is several thousand years older than previously known. While other results are more in line with what we did expect. For example, while caries causing bacteria’s occur in early framers, we instead find periodontitis causing bacteria’s in the hunter gatherers. I will provide some snapshots of how ancient microbial DNA have been studied so far, and what we are doing with such data within our project.

Datum och tid/Time and date
27 november 2020 kl. 13.00-13.40

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Seminariet är på engelska.

Bild på  Anders Götherström
Anders Götherström, Stockholms Universitet
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