Profilbild

Sinisa Bjelic

Lektor, biträdande
Institutionen för kemi och biomedicin Fakulteten för hälso- och livsvetenskap
+46480446264
Spara kontaktuppgifter Ladda ner högupplöst bild

BJELIC LAB

 

 

RESEARCH

 

We are interested in understanding molecular interactions in biology.

To our help we use a combined computational and experimental approach; we often start by applying molecular modelling to build proteins or small-molecules that in theory will interact with a target followed by biochemical validation.

For opportunities in the lab, research interests, etc. please visit our website

http://protein.technology

 

 

TEACHING

 

I am involved in teaching mainly bioichemistry on undergrad level, where I'm also the course respnsible and examiner. We also superwise students on the undergrad and graduate levels mainly with projects that are carried out in our laboratory with focus on protein engineering. 

 

SELECTED PUBLICATIONS

Wijma, H.J., Floor, R.J., Bjelic S., Marrink, S.J, Baker, D, and Janssen, D.B. (2015) Enantioselective enzymes by computational design and in silico screening, Angewandte Chemie, 127, 3797-801.

Liu, Y., Zhang, X., Tan, Y.L., Bhabha, G., Ekiert, D.C., Kipnis, Y., Bjelic, S., Baker, D., Kelly, J.W. (2014) De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters, Journal of American Chemical Society, 136, 13102-5.

Bjelic, S., Kipnis, Y., Wang, L., Pianowski, Z., Vorobiev, S., Su, M., Seetharaman, J., Xiao, R., Kornhaber, G., Hunt, J.F., Tong, L., Hilvert, D., and Baker, D. (2014) Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design, Journal of Molecular Biology, 426, 256-71.

Bjelic, S., Nivon, L.G., Çelebi-Olçum, N., Kiss, G., Rosewall, C.F., Lovick, H.M., Ingalls, E.L., Gallaher, J.L., Seetharaman, J., Lew, S., Montelione, G.T., Hunt, J.F., Michael, F.E., Houk K.N., and Baker, D. (2013) Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction, ACS Chemical Biology, 8, 749-57.

Publikationer

Artikel i tid­skrift (Referee­granskat)

Artikel i tid­skrift (Övrigt veten­skapligt)