Profilbild

Sinisa Bjelic

Lektor, biträdande
Institutionen för kemi och biomedicin Fakulteten för hälso- och livsvetenskap
0480-44 62 64
Norrgård 243
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BJELIC LAB

We are interested in understanding molecular interactions in biology.

To our help we use a combined computational and experimental approach; we often start by applying molecular modelling to build proteins or small-molecules that in theory interact with a target followed by biochemical validation.

For opportunities in the lab, research interests, etc. please visit our website

http://protein.technology

 

SELECTED PUBLICATIONS

Wijma, H.J., Floor, R.J., Bjelic S., Marrink, S.J, Baker, D, and Janssen, D.B. (2015) Enantioselective enzymes by computational design and in silico screening, Angewandte Chemie, 127, 3797-801.

Liu, Y., Zhang, X., Tan, Y.L., Bhabha, G., Ekiert, D.C., Kipnis, Y., Bjelic, S., Baker, D., Kelly, J.W. (2014) De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters, Journal of American Chemical Society, 136, 13102-5.

Bjelic, S., Kipnis, Y., Wang, L., Pianowski, Z., Vorobiev, S., Su, M., Seetharaman, J., Xiao, R., Kornhaber, G., Hunt, J.F., Tong, L., Hilvert, D., and Baker, D. (2014) Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design, Journal of Molecular Biology, 426, 256-71.

Bjelic, S., Nivon, L.G., Çelebi-Olçum, N., Kiss, G., Rosewall, C.F., Lovick, H.M., Ingalls, E.L., Gallaher, J.L., Seetharaman, J., Lew, S., Montelione, G.T., Hunt, J.F., Michael, F.E., Houk K.N., and Baker, D. (2013) Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction, ACS Chemical Biology, 8, 749-57.

Publikationer

Artikel i tid­skrift (Referee­granskat)

Artikel i tid­skrift (Övrigt veten­skapligt)